Okay, how I caused tissue loss was by noogling 8-16 hours a day every day for 6 months, noogling to achieve maximum swelling every day, thinking big swelling was needed for big growth. I never let them turn purple, with the exception of one accident I had with the XL's padding folding over on my right breast and cutting off circulation. It was only that way for less then 5 minutes before I looked and noticed what happened, but I had damaged a blood vessel in the process that was noticeable for almost a year before it finally faded. I had experienced the dreaded red dots several times or more during that first 6 months, but didn't realize until they had shrunk and gotten saggy just how much I was over doing it. I took a three month break do to life getting busy which allowed them time to rest and heal, and when I started up again I took it much slower and easier, 1-3 1 hour sessions per day, using less pressure and during the first month I increased from the deflated 36AA (not even) that I had ended with to a full 36A. Since I have discovered that I seem to have all of my descent growth spurts after taking a break and am currently at a small 36C, possibly in the middle of another growth spurt, so will hopefully be a full 36C soon.
As far as causing tissue damage and reduction the only recommendation I can make is to take it slow and easy. Don't let them turn purple while you're noogling, that's a sign of cutting off circulation which causes the tissue to slowly die and reduce. Also avoid those red dots I dealt with during the first 6 months, those are a sign of broken capillaries (blood blisters), which means you're damaging/breaking the small surface veins which is not good. Above all don't stress about swelling and wanting them to grow overnight, take it slow and easy and have fun with it. I now noogle 1-8 hours a day, depending on how busy I am and if I can make myself keep my hands off them after a couple hours or so of noogling. Most days it's 1-4 hours, but occasionally I can't control myself.
But I control how much pressure I use much better now, so they never turn purple or get the dreaded red dots and they are much happier and larger for it. I also noogle sporadically, sometimes I'll noogle every day for a while then take a short break trying to give them a small growth spurt, and other times I'll just noogle every other day or whenever. I change it up from time to time so they don't get too used to a routine and totally stall on me, but if they do then I just put it up for a couple weeks or so then start up again. Some people have to noogle every day consistently to achieve growth, others like me don't grow that way, you just need to figure out what works for you. But whatever you do, just be careful with them and you'll have great success and happy, healthy breasts.
;D